Summary: Proton MR Spectroscopy was used in 26 concussed adult patients 3-55 days post-injury and 13 controls. Patients completed a symptom questionnaire and those indicating at least one PCS symptom (headache, dizziness, sleep disturbance, memory deficits, blurred vision) were grouped as PCS-positive. All 15 PCS-positive patients had lower white matter NAA than the controls, suggesting that white matter NAA was sensitive to the TBI sequelae associated with common PCS symptoms.
Proton MR spectroscopy correlates diffuse axonal abnormalities with post-concussive symptoms in mild traumatic brain injury
Citation: Kirov, II, Tal, A, Babb, JS, Reaume, J, Bushnik, T, Ashman, T, Flanagan, SR, Grossman, RI and Gonen, O. 2013. Proton MR spectroscopy correlates diffuse axonal abnormalities with post-concussive symptoms in mild traumatic brain injury. J Neurotrauma