Proton MR spectroscopy correlates diffuse axonal abnormalities with post-concussive symptoms in mild traumatic brain injury

Research Type: 
Concussion Literature

Summary: Proton MR Spectroscopy was used in 26 concussed adult patients 3-55 days post-injury and 13 controls. Patients completed a symptom questionnaire and those indicating at least one PCS symptom (headache, dizziness, sleep disturbance, memory deficits, blurred vision) were grouped as PCS-positive. All 15 PCS-positive patients had lower white matter NAA than the controls, suggesting that white matter NAA was sensitive to the TBI sequelae associated with common PCS symptoms.

Citation:  Kirov, II, Tal, A, Babb, JS, Reaume, J, Bushnik, T, Ashman, T, Flanagan, SR, Grossman, RI and Gonen, O. 2013. Proton MR spectroscopy correlates diffuse axonal abnormalities with post-concussive symptoms in mild traumatic brain injury. J Neurotrauma
Category: 
Publication Date: 
2013