CUBIST (Clinical Updates in Brain Injury Science Today)

Launched in May 2017, this series is for health care providers treating service members and veterans with traumatic brain injury (TBI). Each episode offers a brief analysis of current research relevant to clinicians. Listen to or download episodes via SoundCloud, iTunes or Google Play.

In the first episode of CUBIST, we discuss research on how genetics and traumatic brain injury (TBI) interact to impact Alzheimer’s disease risk. Publication discussed: Hayes JP, Logue MW, Sadeh N, et al. Mild traumatic brain injury is associated with reduced cortical thickness in those at risk for Alzheimer's disease.Brain. 2017;140(3):813-825. doi: 10.1093/brain/aww344 PubMed link: https://www.ncbi.nlm.nih.gov/pubmed/28077398

In this episode, Dr. Don Marion discusses two new studies about neurocognitive assessment tools, or NCATs Publications discussed:

  • Cole WR, Arrieux JP, Schwab K, Ivins BJ, Qashu FM, Lewis SC. Test-Retest Reliability of Four Computerized Neurocognitive Assessment Tools in an Active Duty Military Population. Arch Clin Neuropsychol. 2013 Nov;28(7):732-42. doi: 10.1093/arclin/act040. Epub 2013 Jul 2. PubMed link: www.ncbi.nlm.nih.gov/pubmed/23819991
  • Cole WR, Arrieux JP, Ivins BJ, Schwab KA, Qashu FM. A Comparison of Four Computerized Neurocognitive Assessment Tools to a Traditional Neuropsychological Test Battery in Service Members with and without Mild Traumatic Brain Injury. Arch Clin Neuropsychol. 2017 Apr 24:1-18. doi: 10.1093/arclin/acx036. PubMed link: www.ncbi.nlm.nih.gov/pubmed/28444123

In this episode, Dr. Anne Bunner discusses a study about early predictors of long-term outcomes following blast-related concussion.

Publication discussed:
MacDonald C.L., Barber, J., Jordan, M., Johnson, A.M., Dikmen, S., Fann, J.R., & Temkin N. (2017). Early clinical predictors of 5-year outcome after concussive blast traumatic brain injury. JAMA Neurology. Advance online publication. doi: 10.1001/jamaneurol.2017.0143.

PubMed link: www.ncbi.nlm.nih.gov/pubmed/28459953

Link to interview with study’s lead author: www.kgw.com/news/health/study-h…-injuries/441539619

In this episode, Dr. Don Marion discusses a study on the usefulness of wearable sensors to measure head impacts.

Publication discussed:
Cortes, N., Lincoln, A., Myer, G.D., Hepburn, L., Higgins, M., Putukian, M., & Caswell S. (2017). Video analysis verification of head impact events measured by wearable sensors. American Journal of Sports Medicine. Published online. DOI: 10.1177/0363546517706703

PubMed link: www.ncbi.nlm.nih.gov/pubmed/28541813

In this episode, Dr. Anne Bunner and Dr. Don Marion discuss a study comparing rates of depression in men and women following a traumatic brain injury (TBI).

Publication discussed: 
Lavoie, S., Sechrist, S., Quach, N., Ehsanian, R., Duong, T., Gotlib, I. H., & Isaac, L. (2017). Depression in Men and Women One Year Following Traumatic Brain Injury (TBI): A TBI Model Systems Study. Frontiers in Psychology, (8)634, eCollection. doi: 10.3389/fpsyg.2017.00634

PubMed link: www.ncbi.nlm.nih.gov/pubmed/28529492

In this episode, Dr. Don Marion and Dr. Anne Bunner discuss objective and quantifiable imaging markers of traumatic brain injury in relation to aging.

Publication discussed:
Savjani RR, Taylor BA, Acion L, Wilde EA, & Jorge R. Accelerated Changes in Cortical Thickness Measurements with Age in Military Service Members with Traumatic Brain Injury. J Neurotrauma. 2017 Jun 28. doi: 10.1089/neu.2017.5022. [Epub ahead of print]

PubMed link: www.ncbi.nlm.nih.gov/pubmed/28657432

In this episode, Dr. Don Marion and Dr. Anne Bunner discuss a study on the effects of roller coaster rides on the brain.

Publication discussed:
Kuo, C., Wu, L.C., Ye, P.P., Laksari, K., Camarillo, D.B., Kuhl E. (2017). Pilot Findings of Brain Displacements and Deformations during Roller Coaster Rides. Journal of Neurotrauma, epub ahead of print. doi: 10.1089/neu.2016.4893

PubMed link: www.ncbi.nlm.nih.gov/pubmed/28683585