Prevalence of and Screening for Neuroendocrine Dysfunction Post-Mild TBI

July 13, 2017; 1-2:30 p.m. (ET)


Studies of civilian brain injuries from all causes have found a 25-to-50 percent prevalence of chronic endocrine disorders due to damage or disruption of neural and vascular regulation of the pituitary gland. Common symptoms of neuroendocrine dysfunction include cognitive changes, sleep disorders, sexual dysfunction, fatigue, depression, social isolation, harmful changes in body composition, and reduced quality of life.

Mild traumatic brain injury (TBI), or concussion, is the single most frequent injury sustained by U.S. combat troops deployed to Iraq or Afghanistan. The injuries are very often caused by blast waves from improvised explosive devices.

The presenter will discuss a study designed to: 1) determine the prevalence of chronic neuroendocrine dysfunction resulting from explosive blast-related concussions in veterans deployed in Operation Enduring Freedom, Operation Iraqi Freedom, and Operation New Dawn, 2) identify the frequency of occurrence of individual endocrine disorders in these veterans, 3) administer neuropsychological tests and questionnaires to determine the severity of behavioral symptoms, 4) attempt to relate specific symptoms to individual endocrine abnormalities, and 5) offer referral to an endocrinologist to veterans who screen positive for neuroendocrine dysfunction.

At the conclusion of this webinar, participants will be able to:

  • Describe why pituitary function is vulnerable to concussion, particularly blast-related concussion
  • Identify the two endocrine disorders observed most frequently after concussion
  • Articulate how awareness of neuroendocrine dysfunction can effectively assist in evaluating post-mild TBI treatment options
  • Identify five neurobehavioral symptoms frequently observed after post-concussion neuroendocrine dysfunction


Charles W. Wilkinson, Ph.D.
Research Professor Department of Psychiatry and Behavioral Sciences University of Washington School of Medicine Research Physiologist Geriatric Research, Education and Clinical Center Seattle, Washington


Scott D. Blair, J.D.
Director The Pituitary Injury Foundation Seattle, Washington

Continuing Education

Continuing education credit is available from Professional Education Services Group (PESG). You must register by 3 p.m. (ET) July 13, 2017, to qualify for the receipt of continuing education credit.

The awarding of continuing education credit is limited in scope to health care providers who actively provide psychological health and traumatic brain injury care to U.S. active-duty service members, reservists, National Guardsmen, military veterans and their families.

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